BDBM50423622 CHEMBL1614804

SMILES O[C@@H](COc1ccc(Cl)cc1Cl)Cn1c2ccccc2n(CCN2CCCCC2)c1=N

InChI Key InChIKey=QMRFKZWWZBZQKJ-GOSISDBHSA-N

Data  4 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50423622   

TargetCoagulation factor V(Homo sapiens (Human))
Maastricht University

Curated by ChEMBL
LigandPNGBDBM50423622(CHEMBL1614804)
Affinity DataIC50:  1.57E+4nMAssay Description:Inhibition of human factor 5a light chain binding to immobilized phospholipid by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor V(Homo sapiens (Human))
Maastricht University

Curated by ChEMBL
LigandPNGBDBM50423622(CHEMBL1614804)
Affinity DataIC50:  3.24E+4nMAssay Description:Inhibition of factor 5a-mediated prothrombin activation in human plasma by prothrombinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VIII(Homo sapiens (Human))
Maastricht University

Curated by ChEMBL
LigandPNGBDBM50423622(CHEMBL1614804)
Affinity DataIC50:  7.80E+3nMAssay Description:Inhibition of human factor 8 binding to immobilized phospholipid by surface plasmon resonance assayMore data for this Ligand-Target Pair
TargetCoagulation factor V(Homo sapiens (Human))
Maastricht University

Curated by ChEMBL
LigandPNGBDBM50423622(CHEMBL1614804)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of human recombinant factor 5a C2 domain binding to immobilized phospholipid by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed