BindingDB logo
myBDB logout

BDBM50424328 CHEMBL2314500

SMILES: CN1CCCN(CC1)c1nc(N)nc2[nH]ccc12

InChI Key: InChIKey=SUCQRXUPCXTVSO-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50424328   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histamine H4 receptor


(Homo sapiens (Human))
BDBM50424328
PNG
(CHEMBL2314500)
Show SMILES CN1CCCN(CC1)c1nc(N)nc2[nH]ccc12
Show InChI InChI=1S/C12H18N6/c1-17-5-2-6-18(8-7-17)11-9-3-4-14-10(9)15-12(13)16-11/h3-4H,2,5-8H2,1H3,(H3,13,14,15,16)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
8.72E+3n/an/an/an/an/an/an/an/a



KU Leuven

Curated by ChEMBL


Assay Description
Displacement of [3H]Histamine from human histamine H4 receptor expressed in Sf9 cells co-expressing Galphai/o and Gbeta1gamma


Bioorg Med Chem Lett 23: 132-7 (2012)


Article DOI: 10.1016/j.bmcl.2012.10.139
BindingDB Entry DOI: 10.7270/Q28P61TF
More data for this
Ligand-Target Pair