BDBM50425655 CHEMBL2315247

SMILES NC(=N)c1ccc(CNC(=O)[C@@H]2Cc3ccc(NC(=O)CCN4CCCN(CC4)CCC(=O)Nc4ccc(C[C@@H](NS(=O)(=O)Cc5ccccc5)C(=O)N2)cc4)cc3)cc1

InChI Key InChIKey=HNUIINDFHXJLJD-ZESVVUHVSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50425655   

TargetPlasminogen(Homo sapiens (Human))
Philipps University Marburg

Curated by ChEMBL
LigandPNGBDBM50425655(CHEMBL2315247)
Affinity DataKi:  1.30nMAssay Description:Inhibition of human plasmin protease domain using Tos-Gly-Pro-Lys-pNA as substrate by micro plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypsin(Sus scrofa)
Philipps University Marburg

Curated by ChEMBL
LigandPNGBDBM50425655(CHEMBL2315247)
Affinity DataKi:  10nMAssay Description:Inhibition of pig trypsin using CH3SO2-D-Cha-Gly-Arg-pNA as substrate after 5 to 10 mins by micro plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasma kallikrein(Homo sapiens (Human))
Philipps University Marburg

Curated by ChEMBL
LigandPNGBDBM50425655(CHEMBL2315247)
Affinity DataKi:  422nMAssay Description:Inhibition of human plasma kallikrein using H-D-Pro-Phe-Arg-pNA as substrate after 5 to 10 mins by micro plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Philipps University Marburg

Curated by ChEMBL
LigandPNGBDBM50425655(CHEMBL2315247)
Affinity DataKi:  7.80E+3nMAssay Description:Inhibition of human activated protein C using H-D-Lys(Cbz)-Pro-Arg-pNA as substrate after 5 to 10 mins by micro plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Philipps University Marburg

Curated by ChEMBL
LigandPNGBDBM50425655(CHEMBL2315247)
Affinity DataKi:  8.50E+3nMAssay Description:Inhibition of human factor Xa using CH3OCO-D-Cha-Gly-Arg-pNA as substrate after 5 to 10 mins by micro plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Philipps University Marburg

Curated by ChEMBL
LigandPNGBDBM50425655(CHEMBL2315247)
Affinity DataKi:  1.12E+4nMAssay Description:Inhibition of human thrombin using CH3SO2-D-Cha-Gly-Arg-pNA as substrate after 5 to 10 mins by micro plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed