BDBM50425732 ENZALUTAMIDE::US10053433, FC 4.129::US10806720, Compound Enzalutamide::US11230523, Compound Enzalutamide::US11648234, Compound Enzalutamide::US20230382870, Enzalutamide::Xtandi

SMILES: CNC(=O)c1ccc(cc1F)N1C(=S)N(C(=O)C1(C)C)c1ccc(C#N)c(c1)C(F)(F)F

InChI Key: InChIKey=WXCXUHSOUPDCQV-UHFFFAOYSA-N

Data: 15 KI  49 IC50  3 Kd  9 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 79 hits for monomerid = 50425732   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Androgen receptor (Human)	BDBM50425732 (Xtandi | ENZALUTAMIDE | US10053433, FC 4.129 | US1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Human)	BDBM50425732 (Xtandi | ENZALUTAMIDE | US10053433, FC 4.129 | US1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Human)	BDBM50425732 (Xtandi | ENZALUTAMIDE | US10053433, FC 4.129 | US1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	112	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Human)	BDBM50425732 (Xtandi | ENZALUTAMIDE | US10053433, FC 4.129 | US1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	492	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Human)	BDBM50425732 (Xtandi | ENZALUTAMIDE | US10053433, FC 4.129 | US1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.07E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Human)	BDBM50425732 (Xtandi | ENZALUTAMIDE | US10053433, FC 4.129 | US1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.14E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Human)	BDBM50425732 (Xtandi | ENZALUTAMIDE | US10053433, FC 4.129 | US1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	6.52E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Human)	BDBM50425732 (Xtandi | ENZALUTAMIDE | US10053433, FC 4.129 | US1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Human)	BDBM50425732 (Xtandi | ENZALUTAMIDE | US10053433, FC 4.129 | US1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Human)	BDBM50425732 (Xtandi | ENZALUTAMIDE | US10053433, FC 4.129 | US1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	480	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Human)	BDBM50425732 (Xtandi | ENZALUTAMIDE | US10053433, FC 4.129 | US1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	450	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Human)	BDBM50425732 (Xtandi | ENZALUTAMIDE | US10053433, FC 4.129 | US1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Human)	BDBM50425732 (Xtandi | ENZALUTAMIDE | US10053433, FC 4.129 | US1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	2.95E+5	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Human)	BDBM50425732 (Xtandi | ENZALUTAMIDE | US10053433, FC 4.129 | US1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Human)	BDBM50425732 (Xtandi | ENZALUTAMIDE | US10053433, FC 4.129 | US1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	4.02E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Human)	BDBM50425732 (Xtandi | ENZALUTAMIDE | US10053433, FC 4.129 | US1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	117	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Human)	BDBM50425732 (Xtandi | ENZALUTAMIDE | US10053433, FC 4.129 | US1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	75	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Human)	BDBM50425732 (Xtandi | ENZALUTAMIDE | US10053433, FC 4.129 | US1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	117	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Human)	BDBM50425732 (Xtandi | ENZALUTAMIDE | US10053433, FC 4.129 | US1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	62	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein cereblon/CUL4A/AR (Human)	BDBM50425732 (Xtandi | ENZALUTAMIDE | US10053433, FC 4.129 | US1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	99	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Rat)	BDBM50425732 (Xtandi | ENZALUTAMIDE | US10053433, FC 4.129 | US1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	294	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Human)	BDBM50425732 (Xtandi | ENZALUTAMIDE | US10053433, FC 4.129 | US1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Human)	BDBM50425732 (Xtandi | ENZALUTAMIDE | US10053433, FC 4.129 | US1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	361	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Human)	BDBM50425732 (Xtandi | ENZALUTAMIDE | US10053433, FC 4.129 | US1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Human)	BDBM50425732 (Xtandi | ENZALUTAMIDE | US10053433, FC 4.129 | US1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	915	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Human)	BDBM50425732 (Xtandi | ENZALUTAMIDE | US10053433, FC 4.129 | US1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	49	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Human)	BDBM50425732 (Xtandi | ENZALUTAMIDE | US10053433, FC 4.129 | US1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein cereblon/CUL4A/AR (Human)	BDBM50425732 (Xtandi | ENZALUTAMIDE | US10053433, FC 4.129 | US1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	186	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Human)	BDBM50425732 (Xtandi | ENZALUTAMIDE | US10053433, FC 4.129 | US1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.61E+3	n/a	n/a	n/a	n/a	7.5	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein cereblon/CUL4A/AR (Human)	BDBM50425732 (Xtandi | ENZALUTAMIDE | US10053433, FC 4.129 | US1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Human)	BDBM50425732 (Xtandi | ENZALUTAMIDE | US10053433, FC 4.129 | US1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	340	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Human)	BDBM50425732 (Xtandi | ENZALUTAMIDE | US10053433, FC 4.129 | US1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Human)	BDBM50425732 (Xtandi | ENZALUTAMIDE | US10053433, FC 4.129 | US1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	216	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Human)	BDBM50425732 (Xtandi | ENZALUTAMIDE | US10053433, FC 4.129 | US1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	112	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Human)	BDBM50425732 (Xtandi | ENZALUTAMIDE | US10053433, FC 4.129 | US1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.03E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Human)	BDBM50425732 (Xtandi | ENZALUTAMIDE | US10053433, FC 4.129 | US1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	522	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Human)	BDBM50425732 (Xtandi | ENZALUTAMIDE | US10053433, FC 4.129 | US1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Human)	BDBM50425732 (Xtandi | ENZALUTAMIDE | US10053433, FC 4.129 | US1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.97E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Human)	BDBM50425732 (Xtandi | ENZALUTAMIDE | US10053433, FC 4.129 | US1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Rat)	BDBM50425732 (Xtandi | ENZALUTAMIDE | US10053433, FC 4.129 | US1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.32E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Human)	BDBM50425732 (Xtandi | ENZALUTAMIDE | US10053433, FC 4.129 | US1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.34E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Rat)	BDBM50425732 (Xtandi | ENZALUTAMIDE | US10053433, FC 4.129 | US1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.32E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Human)	BDBM50425732 (Xtandi | ENZALUTAMIDE | US10053433, FC 4.129 | US1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Human)	BDBM50425732 (Xtandi | ENZALUTAMIDE | US10053433, FC 4.129 | US1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.26E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Human)	BDBM50425732 (Xtandi | ENZALUTAMIDE | US10053433, FC 4.129 | US1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	216	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Human)	BDBM50425732 (Xtandi | ENZALUTAMIDE | US10053433, FC 4.129 | US1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	216	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Human)	BDBM50425732 (Xtandi | ENZALUTAMIDE | US10053433, FC 4.129 | US1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Rat)	BDBM50425732 (Xtandi | ENZALUTAMIDE | US10053433, FC 4.129 | US1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	361	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Human)	BDBM50425732 (Xtandi | ENZALUTAMIDE | US10053433, FC 4.129 | US1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	180	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Androgen receptor (Human)	BDBM50425732 (Xtandi | ENZALUTAMIDE | US10053433, FC 4.129 | US1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	216	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair