BDBM50425909 SPIRUCHOSTATIN C

SMILES CC[C@H](C)[C@H]1NC(=O)[C@H]2CSSCC\C=C\[C@H](CC(=O)N[C@H](CCS(C)=O)C(=O)N2)OC(=O)C[C@@H]1O

InChI Key InChIKey=DISXKJJDDVRQSD-KLMIADJASA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50425909   

TargetHistone deacetylase 1(Homo sapiens (Human))
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50425909(SPIRUCHOSTATIN C)
Affinity DataIC50:  0.930nMAssay Description:Inhibition of human HDAC1 using Ac-KGLGK(Ac)-MCA as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Mus musculus)
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50425909(SPIRUCHOSTATIN C)
Affinity DataIC50:  320nMAssay Description:Inhibition of mouse HDAC6 using Ac-KGLGK(Ac)-MCA as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed