BDBM50425969 CHEMBL2314698

SMILES COc1ccccc1NC(=O)c1ccc(NC(=O)CCc2nc3ccccc3c(=O)[nH]2)cc1

InChI Key InChIKey=WWKKOAKRYQQEBT-UHFFFAOYSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50425969   

TargetPoly [ADP-ribose] polymerase 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50425969(CHEMBL2314698)
Affinity DataIC50:  931nMAssay Description:Inhibition of PARP2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50425969(CHEMBL2314698)
Affinity DataIC50:  8nMAssay Description:Inhibition of N-terminal His6-tagged human TNKS1 (1091 to 1325 amino acid residues) after 60 mins by autoparsylation assayMore data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50425969(CHEMBL2314698)
Affinity DataIC50:  2nMAssay Description:Inhibition of N-terminal His6-tagged human TNKS2 (946 to 1162 amino acid residues) after 60 mins by autoparsylation assayMore data for this Ligand-Target Pair