BDBM50425970 CHEMBL1257010

SMILES Cc1ccnc2c(NC(=O)c3ccc(cc3)-n3c(O)c4[C@H]5C[C@H](C=C5)c4c3O)cccc12

InChI Key InChIKey=KSLHAODJKMKLGY-CALCHBBNSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50425970   

TargetPoly [ADP-ribose] polymerase tankyrase-1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50425970(CHEMBL1257010)
Affinity DataIC50:  192nMAssay Description:Inhibition of N-terminal His6-tagged human TNKS1 (1091 to 1325 amino acid residues) after 60 mins by autoparsylation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50425970(CHEMBL1257010)
Affinity DataIC50:  36nMAssay Description:Inhibition of N-terminal His6-tagged human TNKS2 (946 to 1162 amino acid residues) after 60 mins by autoparsylation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed