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BDBM50425997 CHEMBL2314719

SMILES: N[C@H](CCN=C(N)N)C(=O)NCCCCCNCCCCCCCNC(=O)[C@@H](NC(=O)Cc1ccc(O)cc1O)c1cnc[nH]1

InChI Key: InChIKey=GPKAPPWMCNVGKQ-IURJKKLANA-N

Data: 2 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50425997   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glutamate [NMDA] receptor subunit epsilon 1/zeta 1


(Rattus norvegicus (Rat)-RAT)
BDBM50425997
PNG
(CHEMBL2314719)
Show SMILES N[C@H](CCN=C(N)N)C(=O)NCCCCCNCCCCCCCNC(=O)[C@@H](NC(=O)Cc1ccc(O)cc1O)c1cnc[nH]1
Show InChI InChI=1/C30H50N10O5/c31-23(11-16-38-30(32)33)28(44)36-14-8-4-6-13-34-12-5-2-1-3-7-15-37-29(45)27(24-19-35-20-39-24)40-26(43)17-21-9-10-22(41)18-25(21)42/h9-10,18-20,23,27,34,41-42H,1-8,11-17,31H2,(H,35,39)(H,36,44)(H,37,45)(H,40,43)(H4,32,33,38)/t23-,27+/s2
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 72n/an/an/an/an/an/a



University of Copenhagen

Curated by ChEMBL


Assay Description
Inhibition of rat GluN1/2A receptor expressed in Xenopus laevis oocyte assessed as glutamate and glycine-induced current at holding potentials from -...


J Med Chem 56: 1171-81 (2013)


Article DOI: 10.1021/jm301602d
BindingDB Entry DOI: 10.7270/Q2S46T9C
More data for this
Ligand-Target Pair
Glutamate receptor 1 (GluA1)


(Rattus norvegicus (Rat))
BDBM50425997
PNG
(CHEMBL2314719)
Show SMILES N[C@H](CCN=C(N)N)C(=O)NCCCCCNCCCCCCCNC(=O)[C@@H](NC(=O)Cc1ccc(O)cc1O)c1cnc[nH]1
Show InChI InChI=1/C30H50N10O5/c31-23(11-16-38-30(32)33)28(44)36-14-8-4-6-13-34-12-5-2-1-3-7-15-37-29(45)27(24-19-35-20-39-24)40-26(43)17-21-9-10-22(41)18-25(21)42/h9-10,18-20,23,27,34,41-42H,1-8,11-17,31H2,(H,35,39)(H,36,44)(H,37,45)(H,40,43)(H4,32,33,38)/t23-,27+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 43n/an/an/an/an/an/a



University of Copenhagen

Curated by ChEMBL


Assay Description
Inhibition of rat GluA1 receptor flip form expressed in Xenopus laevis oocyte assessed as glutamate-induced current at holding potentials from -80 to...


J Med Chem 56: 1171-81 (2013)


Article DOI: 10.1021/jm301602d
BindingDB Entry DOI: 10.7270/Q2S46T9C
More data for this
Ligand-Target Pair