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BDBM50425998 CHEMBL2314927

SMILES: [#7]-[#6@H](-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6](=O)-[#7]-[#6]-[#6]-[#6]-[#6]-[#6]-[#7]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#8])=O)-[#7]-[#6](=O)-[#6]-c1ccc(-[#8])cc1-[#8]

InChI Key: InChIKey=PUWYKGRRMWBUMC-VUEPYQETNA-N

Data: 2 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50425998   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glutamate [NMDA] receptor subunit epsilon 1/zeta 1


(Rattus norvegicus (Rat)-RAT)
BDBM50425998
PNG
(CHEMBL2314927)
Show SMILES N[C@H](CCN=C(N)N)C(=O)NCCCCCNCCCCCCCNC(=O)[C@H](CC(O)=O)NC(=O)Cc1ccc(O)cc1O
Show InChI InChI=1/C29H50N8O7/c30-22(11-16-36-29(31)32)27(43)34-14-8-4-6-13-33-12-5-2-1-3-7-15-35-28(44)23(19-26(41)42)37-25(40)17-20-9-10-21(38)18-24(20)39/h9-10,18,22-23,33,38-39H,1-8,11-17,19,30H2,(H,34,43)(H,35,44)(H,37,40)(H,41,42)(H4,31,32,36)/t22-,23+/s2
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.23E+3n/an/an/an/an/an/a



University of Copenhagen

Curated by ChEMBL


Assay Description
Inhibition of rat GluN1/2A receptor expressed in Xenopus laevis oocyte assessed as glutamate and glycine-induced current at holding potentials from -...


J Med Chem 56: 1171-81 (2013)


Article DOI: 10.1021/jm301602d
BindingDB Entry DOI: 10.7270/Q2S46T9C
More data for this
Ligand-Target Pair
Glutamate receptor 1 (GluA1)


(Rattus norvegicus (Rat))
BDBM50425998
PNG
(CHEMBL2314927)
Show SMILES N[C@H](CCN=C(N)N)C(=O)NCCCCCNCCCCCCCNC(=O)[C@H](CC(O)=O)NC(=O)Cc1ccc(O)cc1O
Show InChI InChI=1/C29H50N8O7/c30-22(11-16-36-29(31)32)27(43)34-14-8-4-6-13-33-12-5-2-1-3-7-15-35-28(44)23(19-26(41)42)37-25(40)17-20-9-10-21(38)18-24(20)39/h9-10,18,22-23,33,38-39H,1-8,11-17,19,30H2,(H,34,43)(H,35,44)(H,37,40)(H,41,42)(H4,31,32,36)/t22-,23+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 167n/an/an/an/an/an/a



University of Copenhagen

Curated by ChEMBL


Assay Description
Inhibition of rat GluA1 receptor flip form expressed in Xenopus laevis oocyte assessed as glutamate-induced current at holding potentials from -80 to...


J Med Chem 56: 1171-81 (2013)


Article DOI: 10.1021/jm301602d
BindingDB Entry DOI: 10.7270/Q2S46T9C
More data for this
Ligand-Target Pair