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BDBM50426142 CHEMBL1341853

SMILES: [#7]-[#6](=S)-[#7]\[#7]=[#6](\[#6]-c1ccccc1)-[#6]-c1ccccc1

InChI Key: InChIKey=SEPLCPIJGDUUHY-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50426142   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cathepsin K


(Homo sapiens (Human))
BDBM50426142
PNG
(CHEMBL1341853)
Show SMILES NC(=S)NN=C(Cc1ccccc1)Cc1ccccc1
Show InChI InChI=1S/C16H17N3S/c17-16(20)19-18-15(11-13-7-3-1-4-8-13)12-14-9-5-2-6-10-14/h1-10H,11-12H2,(H3,17,19,20)
PDB
MMDB

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a>3.00E+4n/an/an/an/an/an/a



MSD Animal Health Innovation GmbH

Curated by ChEMBL


Assay Description
Inhibition of human recombinant His-tagged cathepsin K using Cbz-Phe-Arg-AMC as substrate incubated for 30 mins prior to substrate addition by FRET a...


J Med Chem 56: 1478-90 (2013)


Article DOI: 10.1021/jm3013932
BindingDB Entry DOI: 10.7270/Q2W09774
More data for this
Ligand-Target Pair