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BDBM50426144 CHEMBL2316597

SMILES: CC(C)(C)NC(=O)C1C2C3CCCCC3(NCC1=O)Oc1ccccc21

InChI Key: InChIKey=HHSFJHANGGIQHQ-UHFFFAOYNA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50426144   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cathepsin K


(Homo sapiens (Human))
BDBM50426144
PNG
(CHEMBL2316597)
Show SMILES CC(C)(C)NC(=O)C1C2C3CCCCC3(NCC1=O)Oc1ccccc21
Show InChI InChI=1/C21H28N2O3/c1-20(2,3)23-19(25)18-15(24)12-22-21-11-7-6-9-14(21)17(18)13-8-4-5-10-16(13)26-21/h4-5,8,10,14,17-18,22H,6-7,9,11-12H2,1-3H3,(H,23,25)
PDB
MMDB

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PC cid
PC sid
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Article
PubMed
n/an/a>3.00E+4n/an/an/an/an/an/a



MSD Animal Health Innovation GmbH

Curated by ChEMBL


Assay Description
Inhibition of human recombinant His-tagged cathepsin K using Cbz-Phe-Arg-AMC as substrate incubated for 30 mins prior to substrate addition by FRET a...


J Med Chem 56: 1478-90 (2013)


Article DOI: 10.1021/jm3013932
BindingDB Entry DOI: 10.7270/Q2W09774
More data for this
Ligand-Target Pair