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BDBM50426167 CHEMBL2316590

SMILES: CC(C)CC(NC(=O)N1CCNCC1)C(=O)NC(CCc1ccccc1)C=CS(=O)(=O)c1ccccc1

InChI Key: InChIKey=AXSMOEDHJONYII-HKWRFOASNA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50426167   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cathepsin K


(Homo sapiens (Human))
BDBM50426167
PNG
(CHEMBL2316590)
Show SMILES CC(C)CC(NC(=O)N1CCNCC1)C(=O)NC(CCc1ccccc1)C=CS(=O)(=O)c1ccccc1
Show InChI InChI=1/C28H38N4O4S/c1-22(2)21-26(31-28(34)32-18-16-29-17-19-32)27(33)30-24(14-13-23-9-5-3-6-10-23)15-20-37(35,36)25-11-7-4-8-12-25/h3-12,15,20,22,24,26,29H,13-14,16-19,21H2,1-2H3,(H,30,33)(H,31,34)/b20-15-
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MMDB

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Similars

Article
PubMed
12n/an/an/an/an/an/an/an/a



MSD Animal Health Innovation GmbH

Curated by ChEMBL


Assay Description
Inhibition of human cathepsin K


J Med Chem 56: 1478-90 (2013)


Article DOI: 10.1021/jm3013932
BindingDB Entry DOI: 10.7270/Q2W09774
More data for this
Ligand-Target Pair