BDBM50426560 CHEMBL2323963

SMILES Cc1cnc(C)c2nc(nn12)-c1ccn2cc(nc2c1)-c1cccc(c1)N1CC[C@H](F)C1

InChI Key InChIKey=TZQFQCFDWSALEU-IBGZPJMESA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50426560   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50426560(CHEMBL2323963)
Affinity DataIC50:  0.160nMAssay Description:Inhibition of PDE10A (unknown origin) by LE-PDE10A inhibition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50426560(CHEMBL2323963)
Affinity DataIC50:  0.160nMpH: 7.4Assay Description:The PDE10 inhibition assay in 384-well plates was conducted to identify substances for the inhibition of cyclic nucleotide hydrolysis by the PDE10 en...More data for this Ligand-Target Pair
In DepthDetails US Patent