BDBM50426600 CHEMBL2325896

SMILES O=C(N[C@H](C1CC1)C(=O)N1CC(C1)C#N)c1c[nH]c2ncc(nc12)C1CC1

InChI Key InChIKey=MIHIZGXUSZQEJD-OAHLLOKOSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50426600   

TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50426600(CHEMBL2325896)
Affinity DataIC50:  206nMAssay Description:Inhibition of JAK2 in human PBMC expressing CD14 assessed as inhibition of GM-CSF-stimulated STAT5a phosphorylation after 30 mins by flow cytometric ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed