BDBM50426617 CHEMBL2325902

SMILES CC[C@H](C)NC(=O)c1c[nH]c2ncc(nc12)C1CC1

InChI Key InChIKey=VAZJXEJUMZTDQP-QMMMGPOBSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50426617   

TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50426617(CHEMBL2325902)
Affinity DataIC50:  76nMAssay Description:Inhibition of JAK1 (unknown origin)-mediated phosphorylation of Biotin-KAIETDKEYYTVKD incubated for 10 mins prior to substrate addition measured afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50426617(CHEMBL2325902)
Affinity DataIC50:  9.60nMAssay Description:Inhibition of JAK3 (unknown origin)-mediated phosphorylation of Biotin-KAIETDKEYYTVKD incubated for 10 mins prior to substrate addition measured afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50426617(CHEMBL2325902)
Affinity DataIC50:  44nMAssay Description:Inhibition of JAK2 (unknown origin)-mediated phosphorylation of Biotin-KAIETDKEYYTVKD incubated for 10 mins prior to substrate addition measured afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed