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BDBM50426771 CHEMBL2322440

SMILES: CCc1nc2ccn(CC(O)=O)c(=O)c2n1[C@H]1CCc2cc(ccc12)-c1ccccc1-c1nnn[nH]1

InChI Key: InChIKey=CSGHOMXVYIMAHV-RNZRUAGMNA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50426771   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Peroxisome proliferator-activated receptor


(Homo sapiens (Human))
BDBM50426771
PNG
(CHEMBL2322440)
Show SMILES CCc1nc2ccn(CC(O)=O)c(=O)c2n1[C@H]1CCc2cc(ccc12)-c1ccccc1-c1nnn[nH]1
Show InChI InChI=1/C26H23N7O3/c1-2-22-27-20-11-12-32(14-23(34)35)26(36)24(20)33(22)21-10-8-16-13-15(7-9-18(16)21)17-5-3-4-6-19(17)25-28-30-31-29-25/h3-7,9,11-13,21H,2,8,10,14H2,1H3,(H,34,35)(H,28,29,30,31)/t21-/s2
PDB
MMDB

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KEGG

UniProtKB/SwissProt

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DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a>1.00E+5n/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Partial agonist activity at human PPARgamma-LBD/Gal4 DNA binding domain by transactivation assay


Bioorg Med Chem Lett 23: 767-72 (2013)


Article DOI: 10.1016/j.bmcl.2012.11.088
BindingDB Entry DOI: 10.7270/Q2542PW7
More data for this
Ligand-Target Pair
Angiotensin II receptor


(Homo sapiens (Human))
BDBM50426771
PNG
(CHEMBL2322440)
Show SMILES CCc1nc2ccn(CC(O)=O)c(=O)c2n1[C@H]1CCc2cc(ccc12)-c1ccccc1-c1nnn[nH]1
Show InChI InChI=1/C26H23N7O3/c1-2-22-27-20-11-12-32(14-23(34)35)26(36)24(20)33(22)21-10-8-16-13-15(7-9-18(16)21)17-5-3-4-6-19(17)25-28-30-31-29-25/h3-7,9,11-13,21H,2,8,10,14H2,1H3,(H,34,35)(H,28,29,30,31)/t21-/s2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 348n/an/an/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Displacement of [125I]Tyr4-Sar1,Ile8-Angiotensin II from human Angiotensin 1 receptor after


Bioorg Med Chem Lett 23: 767-72 (2013)


Article DOI: 10.1016/j.bmcl.2012.11.088
BindingDB Entry DOI: 10.7270/Q2542PW7
More data for this
Ligand-Target Pair