BDBM50426799 CHEMBL2322771
SMILES CN(C(=O)c1cc2CCOc3ccccc3-c2s1)c1ccc(F)cc1F
InChI Key InChIKey=LTFMGVLICZZZOJ-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50426799
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Genentech
Curated by ChEMBL
Genentech
Curated by ChEMBL
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of PI3Kalpha-mediated AKT Ser 473 phosphorylation in human PC3 cellsMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Genentech
Curated by ChEMBL
Genentech
Curated by ChEMBL
Affinity DataIC50: 52nMAssay Description:Inhibition of recombinant PI3Kalpha (unknown origin)-mediated 3,4,5-inositoltriphosphate formation after 30 mins by TAMRA-PIP3-based competitive fluo...More data for this Ligand-Target Pair