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BDBM50426832 CHEMBL2323146

SMILES: CC1=NN2C(C1)c1ccc(C)cc1OCC2=O

InChI Key: InChIKey=BCHOUVSVNDAKSX-UHFFFAOYNA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50426832   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Telomerase reverse transcriptase


(Homo sapiens (Human))
BDBM50426832
PNG
(CHEMBL2323146)
Show SMILES CC1=NN2C(C1)c1ccc(C)cc1OCC2=O
Show InChI InChI=1/C13H14N2O2/c1-8-3-4-10-11-6-9(2)14-15(11)13(16)7-17-12(10)5-8/h3-5,11H,6-7H2,1-2H3
PDB

NCI pathway
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KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.19E+4n/an/an/an/an/an/a



Guizhou University

Curated by ChEMBL


Assay Description
Inhibition of telomerase-mediated supercoiling activity in human MGC803 cells after 24 hrs by TRAP-PCR-ELISA assay


Bioorg Med Chem Lett 23: 720-3 (2013)


Article DOI: 10.1016/j.bmcl.2012.11.101
BindingDB Entry DOI: 10.7270/Q2HD7X07
More data for this
Ligand-Target Pair