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BDBM50427169 CHEMBL2324114

SMILES: CN(CC1COCCO1)C(=O)Cc1ccc2ccc3ncc(cc3c(=O)c2c1)-c1cnn(C)c1

InChI Key: InChIKey=UIQYIYNZQLDTDH-UHFFFAOYNA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50427169   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50427169
PNG
(CHEMBL2324114)
Show SMILES CN(CC1COCCO1)C(=O)Cc1ccc2ccc3ncc(cc3c(=O)c2c1)-c1cnn(C)c1
Show InChI InChI=1/C26H26N4O4/c1-29(15-21-16-33-7-8-34-21)25(31)10-17-3-4-18-5-6-24-23(26(32)22(18)9-17)11-19(12-27-24)20-13-28-30(2)14-20/h3-6,9,11-14,21H,7-8,10,15-16H2,1-2H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 3.19E+3n/an/an/an/an/an/a



Merck& Co., Inc.

Curated by ChEMBL


Assay Description
Inhibition of c-MET (unknown origin)-catalyzed N-biotinylated EQEDEPEGDYFEWLECONH2 phosphorylation by TR-FRET assay


J Med Chem 56: 2294-310 (2013)


Article DOI: 10.1021/jm301619u
BindingDB Entry DOI: 10.7270/Q21837VX
More data for this
Ligand-Target Pair