BDBM50427787 CHEMBL2325198

SMILES O=C(NCC(=O)N1CCCCC1)Nc1ccc2nnsc2c1

InChI Key InChIKey=MYTRGTBDVGKKRO-UHFFFAOYSA-N

Data  2 IC50  1 Kd

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50427787   

TargetProtein arginine N-methyltransferase 3 [N508S](Homo sapiens (Human))
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50427787(CHEMBL2325198)
Affinity DataIC50:  230nMAssay Description:Inhibition of PRMT3 (unknown origin) using histone H4 (1 to 24) as substrate after 1 hr by scintillation proximity assay in presence of [3H]-S-adenos...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain adjacent to zinc finger domain protein 1A(Homo sapiens)
Sichuan Provincial People'S Hospital

Curated by ChEMBL
LigandPNGBDBM50427787(CHEMBL2325198)
Affinity DataKd:  2.56E+4nMAssay Description:Binding affinity to recombinant human N-terminal His6-tagged BAZ1A (1446 to 1516 residues) expressed in Escherichia coli BL21 (DE3) cells by MST assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 3(Homo sapiens)
Icahn School of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50427787(CHEMBL2325198)
Affinity DataIC50:  134nMAssay Description:Inhibition of PRMT3 (unknown origin) using C-terminally biotinylated histone H4 as substrate in presence of [3H]S-adenosylmethionine by scintillation...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed