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BDBM50428321 CHEMBL2338387

SMILES: OC[C@H](NC(=O)[C@H]1C[C@@H]1c1ccc(F)cc1)c1ccc(OC2CCC2)nc1

InChI Key: InChIKey=FCMRWVBXSWDTIB-FPICWYNDNA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50428321   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Neuronal acetylcholine receptor subunit alpha-7


(Homo sapiens (Human))
BDBM50428321
PNG
(CHEMBL2338387)
Show SMILES OC[C@H](NC(=O)[C@H]1C[C@@H]1c1ccc(F)cc1)c1ccc(OC2CCC2)nc1
Show InChI InChI=1/C21H23FN2O3/c22-15-7-4-13(5-8-15)17-10-18(17)21(26)24-19(12-25)14-6-9-20(23-11-14)27-16-2-1-3-16/h4-9,11,16-19,25H,1-3,10,12H2,(H,24,26)/t17-,18+,19+/s2
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 790n/an/an/an/a



Dart Neuroscience LLC

Curated by ChEMBL


Assay Description
Positive allosteric modulator activity at human alpha7 nAChR expressed in rat GH4C1 cells assessed as potentiation of acetylcholine-induced response ...


ACS Med Chem Lett 4: 319-20 (2013)


Article DOI: 10.1021/ml400054p
BindingDB Entry DOI: 10.7270/Q2FX7BS2
More data for this
Ligand-Target Pair