BDBM50428839 CHEMBL2337529

SMILES COc1cc(\C=C(/C#N)C(=O)Nc2ccc(cc2)S(N)(=O)=O)ccc1O

InChI Key InChIKey=GHISFLWEZHJNCZ-XYOKQWHBSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50428839   

TargetCarbonic anhydrase 12(Homo sapiens (Human))
Salman Bin Abdulaziz University

Curated by ChEMBL
LigandPNGBDBM50428839(CHEMBL2337529)
Affinity DataKi:  5.20nMAssay Description:Inhibition of human carbonic anhydrase 12 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Salman Bin Abdulaziz University

Curated by ChEMBL
LigandPNGBDBM50428839(CHEMBL2337529)
Affinity DataKi:  5.40nMAssay Description:Inhibition of human carbonic anhydrase 9 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Salman Bin Abdulaziz University

Curated by ChEMBL
LigandPNGBDBM50428839(CHEMBL2337529)
Affinity DataKi:  6nMAssay Description:Inhibition of human carbonic anhydrase 2 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Salman Bin Abdulaziz University

Curated by ChEMBL
LigandPNGBDBM50428839(CHEMBL2337529)
Affinity DataKi:  33nMAssay Description:Inhibition of human carbonic anhydrase 1 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed