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BDBM50429167 CHEMBL2336704

SMILES: C[C@H]1c2[nH]c3ccc4ccccc4c3c2Cc2c(O)n(C)c(=S)n12

InChI Key: InChIKey=JMHMLIAFCYOQEG-JTQLQIEISA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50429167   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Indoleamine 2,3-dioxygenase


(Homo sapiens (Human))
BDBM50429167
PNG
(CHEMBL2336704)
Show SMILES C[C@H]1c2[nH]c3ccc4ccccc4c3c2Cc2c(O)n(C)c(=S)n12
Show InChI InChI=1S/C19H17N3OS/c1-10-17-13(9-15-18(23)21(2)19(24)22(10)15)16-12-6-4-3-5-11(12)7-8-14(16)20-17/h3-8,10,20,23H,9H2,1-2H3/t10-/m0/s1
PDB
MMDB

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Similars

Article
PubMed
n/an/a 8.20E+4n/an/an/an/an/an/a



Toho University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant IDO assessed as inhibition of indoleamine 2,3-dioxygenase to kynurenine conversion after 60 mins by HPLC analysis


Bioorg Med Chem 21: 1159-65 (2013)


Article DOI: 10.1016/j.bmc.2012.12.028
BindingDB Entry DOI: 10.7270/Q2RX9DDH
More data for this
Ligand-Target Pair