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BDBM50429308 CHEMBL2334157

SMILES: O=C(C1CC1)N1CCC[C@@H](C1)c1nc(no1)-c1ccccc1

InChI Key: InChIKey=RQSZLEYSAWZBFB-AWEZNQCLSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50429308   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
11-beta-hydroxysteroid dehydrogenase 1


(Homo sapiens (Human))
BDBM50429308
PNG
(CHEMBL2334157)
Show SMILES O=C(C1CC1)N1CCC[C@@H](C1)c1nc(no1)-c1ccccc1
Show InChI InChI=1S/C17H19N3O2/c21-17(13-8-9-13)20-10-4-7-14(11-20)16-18-15(19-22-16)12-5-2-1-3-6-12/h1-3,5-6,13-14H,4,7-11H2/t14-/m0/s1
PDB
MMDB

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PC cid
PC sid
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Similars

Article
PubMed
n/an/a 92n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of human 11-beta HSD1 transfected in HEK293 cell microsomes assessed as decrease in [3H]cortisol generation using [3H]cortisone as substra...


Eur J Med Chem 62: 1-10 (2013)


Article DOI: 10.1016/j.ejmech.2012.12.059
BindingDB Entry DOI: 10.7270/Q2GH9K9M
More data for this
Ligand-Target Pair