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BDBM50429629 CHEMBL2334971

SMILES: Cc1nc2ccc(C)cn2c1-c1ccnc(N)n1

InChI Key: InChIKey=WQMWNAGFFRUYJC-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50429629   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mitogen-activated protein kinase kinase kinase 14


(Homo sapiens (Human))
BDBM50429629
PNG
(CHEMBL2334971)
Show SMILES Cc1nc2ccc(C)cn2c1-c1ccnc(N)n1
Show InChI InChI=1S/C13H13N5/c1-8-3-4-11-16-9(2)12(18(11)7-8)10-5-6-15-13(14)17-10/h3-7H,1-2H3,(H2,14,15,17)
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Similars

Article
PubMed
n/an/a 4.20E+4n/an/an/an/an/an/a



Amgen Inc

Curated by ChEMBL


Assay Description
Inhibition of NIK (unknown origin) autophosphorylation after 1 hr by chemiluminescent assay


Bioorg Med Chem Lett 23: 1238-44 (2013)


Article DOI: 10.1016/j.bmcl.2013.01.012
BindingDB Entry DOI: 10.7270/Q2J967RQ
More data for this
Ligand-Target Pair