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BDBM50429638 CHEMBL2334962

SMILES: Cc1[nH]c2ccc(Cl)cc2c1-c1ccnc(N)n1

InChI Key: InChIKey=ZOZOVZWABDIYMR-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50429638   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
NF-kappa-beta-inducing kinase (NF-kB)


(Homo sapiens (Human))
BDBM50429638
PNG
(CHEMBL2334962)
Show SMILES Cc1[nH]c2ccc(Cl)cc2c1-c1ccnc(N)n1
Show InChI InChI=1S/C13H11ClN4/c1-7-12(11-4-5-16-13(15)18-11)9-6-8(14)2-3-10(9)17-7/h2-6,17H,1H3,(H2,15,16,18)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 300n/an/an/an/an/an/a



Amgen Inc

Curated by ChEMBL


Assay Description
Inhibition of NIK (unknown origin) autophosphorylation after 1 hr by chemiluminescent assay


Bioorg Med Chem Lett 23: 1238-44 (2013)


Article DOI: 10.1016/j.bmcl.2013.01.012
BindingDB Entry DOI: 10.7270/Q2J967RQ
More data for this
Ligand-Target Pair