BDBM50430138 CHEMBL2338248

SMILES COc1ccccc1-n1ncc2c1C(C)(C)CCN([C@H]1C3CC4CC1C[C@@](O)(C4)C3)C2=O

InChI Key InChIKey=VZUTXOBHVIWIHK-WAXDZURTSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50430138   

Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50430138(CHEMBL2338248)
Affinity DataIC50:  11nMAssay Description:Inhibition of 11beta-HSD1 in human liver microsomes using cortisone and NADPH as substrate by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50430138(CHEMBL2338248)
Affinity DataIC50:  18nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in HEK293 cells using cortisone and NADPH as substrate by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed