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BDBM50430173 CHEMBL2313097

SMILES: Cc1c(cc(NC(=O)c2cc(Cl)ccc2O)cc1C(F)(F)F)C(F)(F)F

InChI Key: InChIKey=MIWDTWVEGVCOSG-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50430173   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Transmembrane protease serine 4


(Homo sapiens (Human))
BDBM50430173
PNG
(CHEMBL2313097)
Show SMILES Cc1c(cc(NC(=O)c2cc(Cl)ccc2O)cc1C(F)(F)F)C(F)(F)F
Show InChI InChI=1S/C16H10ClF6NO2/c1-7-11(15(18,19)20)5-9(6-12(7)16(21,22)23)24-14(26)10-4-8(17)2-3-13(10)25/h2-6,25H,1H3,(H,24,26)
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.00E+4n/an/an/an/an/an/a



Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL


Assay Description
Inhibition of N-terminal His6-tagged recombinant TMPRSS4 (unknown origin) fused with enterokinase cleavage sequence DYKDDDGDYKDDDDK expressed in Esch...


Bioorg Med Chem Lett 23: 1748-51 (2013)


Article DOI: 10.1016/j.bmcl.2013.01.055
BindingDB Entry DOI: 10.7270/Q2057H8S
More data for this
Ligand-Target Pair