BDBM50430630 CHEMBL1650595::US8741944, 70

SMILES NCC(=O)Nc1ccc(cc1)-n1nc(cc1-c1ccc2c(ccc3ccccc23)c1)C(F)(F)F

InChI Key InChIKey=YULUCECVQOCQFQ-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50430630   

Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50430630(CHEMBL1650595 | US8741944, 70)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of recombinant PDK1 (unknown origin) using RPRAATF peptide as substrate assessed as substrate phosphorylation by scintillation counting an...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50430630(CHEMBL1650595 | US8741944, 70)
Affinity DataIC50:  5.00E+3nMAssay Description:PDK-1 kinase activity This in vitro assay was performed using a PDK-1 kinase assay kit (Upstate, Lake Placid, N.Y.) according to the vendor's ins...More data for this Ligand-Target Pair
In DepthDetails US Patent