BDBM50430875 CHEMBL2336005::US9062066, LCB 03-0110
SMILES Oc1cccc(Nc2ccnc3cc(sc23)-c2cccc(CN3CCOCC3)c2)c1
InChI Key InChIKey=ZCWXCBKGPJOAFQ-UHFFFAOYSA-N
Data 19 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 19 hits for monomerid = 50430875
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Korea Institute Of Science And Technology
US Patent
Korea Institute Of Science And Technology
US Patent
Affinity DataIC50: 1.30nMpH: 8.0Assay Description:The inhibitory activity measurement against the kinases mentioned above was measured in the kinase inhibition reaction mixture containing 2 ul purifi...More data for this Ligand-Target Pair
TargetEpithelial discoidin domain-containing receptor 1(Homo sapiens (Human))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 164nMAssay Description:Inhibition of type 1 collagen-induced autophosphorylation of human recombinant DDR1 expressed in HEK293 cells by Western blotting analysisMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Lyn(Homo sapiens (Human))
Korea Institute Of Science And Technology
US Patent
Korea Institute Of Science And Technology
US Patent
Affinity DataIC50: 4.30nMpH: 8.0Assay Description:The inhibitory activity measurement against the kinases mentioned above was measured in the kinase inhibition reaction mixture containing 2 ul purifi...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase Lyn(Homo sapiens (Human))
Korea Institute Of Science And Technology
US Patent
Korea Institute Of Science And Technology
US Patent
Affinity DataIC50: 2.30nMpH: 8.0Assay Description:The inhibitory activity measurement against the kinases mentioned above was measured in the kinase inhibition reaction mixture containing 2 ul purifi...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase Yes(Homo sapiens (Human))
Korea Institute Of Science And Technology
US Patent
Korea Institute Of Science And Technology
US Patent
Affinity DataIC50: 2.10nMpH: 8.0Assay Description:The inhibitory activity measurement against the kinases mentioned above was measured in the kinase inhibition reaction mixture containing 2 ul purifi...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase Fgr(Homo sapiens (Human))
Korea Institute Of Science And Technology
US Patent
Korea Institute Of Science And Technology
US Patent
Affinity DataIC50: 3.70nMpH: 8.0Assay Description:The inhibitory activity measurement against the kinases mentioned above was measured in the kinase inhibition reaction mixture containing 2 ul purifi...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase HCK(Homo sapiens (Human))
Korea Institute Of Science And Technology
US Patent
Korea Institute Of Science And Technology
US Patent
Affinity DataIC50: 4.40nMpH: 8.0Assay Description:The inhibitory activity measurement against the kinases mentioned above was measured in the kinase inhibition reaction mixture containing 2 ul purifi...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase HCK(Homo sapiens (Human))
Korea Institute Of Science And Technology
US Patent
Korea Institute Of Science And Technology
US Patent
Affinity DataIC50: 50.7nMpH: 8.0Assay Description:The inhibitory activity measurement against the kinases mentioned above was measured in the kinase inhibition reaction mixture containing 2 ul purifi...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Korea Institute Of Science And Technology
US Patent
Korea Institute Of Science And Technology
US Patent
Affinity DataIC50: 17.7nMpH: 8.0Assay Description:The inhibitory activity measurement against the kinases mentioned above was measured in the kinase inhibition reaction mixture containing 2 ul purifi...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Korea Institute Of Science And Technology
US Patent
Korea Institute Of Science And Technology
US Patent
Affinity DataIC50: 25.2nMpH: 8.0Assay Description:The inhibitory activity measurement against the kinases mentioned above was measured in the kinase inhibition reaction mixture containing 2 ul purifi...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Korea Institute Of Science And Technology
US Patent
Korea Institute Of Science And Technology
US Patent
Affinity DataIC50: 4.60nMpH: 8.0Assay Description:The inhibitory activity measurement against the kinases mentioned above was measured in the kinase inhibition reaction mixture containing 2 ul purifi...More data for this Ligand-Target Pair
TargetEphrin type-A receptor 3(Homo sapiens (Human))
Korea Institute Of Science And Technology
US Patent
Korea Institute Of Science And Technology
US Patent
Affinity DataIC50: 5.10nMpH: 8.0Assay Description:The inhibitory activity measurement against the kinases mentioned above was measured in the kinase inhibition reaction mixture containing 2 ul purifi...More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Korea Institute Of Science And Technology
US Patent
Korea Institute Of Science And Technology
US Patent
Affinity DataIC50: 26.1nMpH: 8.0Assay Description:The inhibitory activity measurement against the kinases mentioned above was measured in the kinase inhibition reaction mixture containing 2 ul purifi...More data for this Ligand-Target Pair
TargetDiscoidin domain-containing receptor 2(Homo sapiens (Human))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 171nMAssay Description:Inhibition of human DDR2 expressed in HEK293 cells assessed as reduction in collagen-1-induced receptor auto-phosphorylation by Western blot methodMore data for this Ligand-Target Pair
TargetEpithelial discoidin domain-containing receptor 1(Homo sapiens (Human))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 164nMAssay Description:Inhibition of human DDR1b expressed in HEK293 cells assessed as reduction in collagen-1-induced receptor auto-phosphorylation by Western blot methodMore data for this Ligand-Target Pair
TargetDiscoidin domain-containing receptor 2(Homo sapiens (Human))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 145nMAssay Description:Inhibition of recombinant non-activated DDR2 tyrosine kinase domain (unknown origin) using histone H2B peptide substrate and [32P]ATP incubated for 1...More data for this Ligand-Target Pair
TargetDiscoidin domain-containing receptor 2(Homo sapiens (Human))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of recombinant activated DDR2 tyrosine kinase domain (unknown origin) using histone H2B peptide substrate and [32P]ATP incubated for 15 mi...More data for this Ligand-Target Pair
TargetDiscoidin domain-containing receptor 2(Homo sapiens (Human))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 171nMAssay Description:Inhibition of type 1 collagen-induced autophosphorylation of human recombinant DDR2 expressed in HEK293 cells by Western blotting analysisMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Korea Institute Of Science And Technology
US Patent
Korea Institute Of Science And Technology
US Patent
Affinity DataIC50: 21.6nMpH: 8.0Assay Description:The inhibitory activity measurement against the kinases mentioned above was measured in the kinase inhibition reaction mixture containing 2 ul purifi...More data for this Ligand-Target Pair