BDBM50431084 CHEMBL2338802::US10202399, Example 14

SMILES COc1ccc(CCc2cc(O)c(=O)[nH]n2)cc1

InChI Key InChIKey=YDXOZGMGXDPRQB-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50431084   

TargetD-amino-acid oxidase(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50431084(CHEMBL2338802 | US10202399, Example 14)
Affinity DataIC50:  2.90nMAssay Description:Inhibition of human recombinant DAAO after 30 mins by plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-amino-acid oxidase(Rattus norvegicus (rat))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50431084(CHEMBL2338802 | US10202399, Example 14)
Affinity DataIC50:  3.80nMAssay Description:Inhibition of rat full length DAAO overexpressed in HEK293 cells after 30 mins by plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-amino-acid oxidase(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50431084(CHEMBL2338802 | US10202399, Example 14)
Affinity DataIC50:  2.90nMAssay Description:The DAAO inhibitory activity was measured by assaying the amount of hydrogen peroxide (H2O2) produced by reacting DAAO protein with flavin adenine di...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD-amino-acid oxidase(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50431084(CHEMBL2338802 | US10202399, Example 14)
Affinity DataIC50:  10nMAssay Description:Inhibition of human full length DAAO overexpressed in HEK293 cells after 30 mins by plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-amino-acid oxidase(Mus musculus)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50431084(CHEMBL2338802 | US10202399, Example 14)
Affinity DataIC50:  3.60nMAssay Description:Inhibition of mouse full length DAAO overexpressed in HEK293 cells after 30 mins by plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed