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BDBM50431248 CHEMBL2333060

SMILES: CCCCCCCCNC(=O)n1cc(F)c(=O)[nH]c1=O

InChI Key: InChIKey=JNQHBKLRBXQHJO-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50431248   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Acid ceramidase (AC)


(Rattus norvegicus (Rat))
BDBM50431248
PNG
(CHEMBL2333060)
Show SMILES CCCCCCCCNC(=O)n1cc(F)c(=O)[nH]c1=O
Show InChI InChI=1S/C13H20FN3O3/c1-2-3-4-5-6-7-8-15-12(19)17-9-10(14)11(18)16-13(17)20/h9H,2-8H2,1H3,(H,15,19)(H,16,18,20)
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 46n/an/an/an/an/an/a



Fondazione Istituto Italiano di Tecnologia

Curated by ChEMBL


Assay Description
Inhibition of rat recombinant acid ceramidase expressed in human HEK293 cells using N-lauroylceramide as substrate incubated for 30 mins prior to sub...


J Med Chem 56: 3518-30 (2013)

More data for this
Ligand-Target Pair