BDBM50431391 CHEMBL2348852

SMILES CC(C)NC(=O)c1c[nH]c2ncc(nc12)-c1nn(C)c2cc(Cl)ccc12

InChI Key InChIKey=QROQIIGDSDRLDZ-UHFFFAOYSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50431391   

TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50431391(CHEMBL2348852)
Affinity DataIC50:  36nMAssay Description:Inhibition of human recombinant truncated SYK (360 to 365 amino acid residues) using N-terminally biotinylated EPEGDYEEVLE peptide as substrate asses...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50431391(CHEMBL2348852)
Affinity DataIC50:  1.66E+4nMAssay Description:Inhibition of SYK in human whole bloodMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50431391(CHEMBL2348852)
Affinity DataIC50:  512nMAssay Description:Inhibition of SYK in human Ramos cellsMore data for this Ligand-Target Pair