BDBM50431520 CHEMBL2348863

SMILES CC(C)(O)c1ccc(-c2cnc3[nH]c(=O)n(CC4CCOCC4)c3n2)cn1

InChI Key InChIKey=WVFYKPHMSAZPQO-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50431520   

TargetSerine/threonine-protein kinase mTOR(Human)
Celgene

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50431520BDBM50431520(CHEMBL2348863)
Affinity DataIC50: 176nMAssay Description:Inhibition of recombinant mTOR (unknown origin) using GST-p70S6 as substrate after 60 mins by TR-FRET analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetTarget of rapamycin complex subunit LST8(Human)
University of Hradec Kralove

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50431520BDBM50431520(CHEMBL2348863)
Affinity DataIC50: 176nMAssay Description:Inhibition of mTORC1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
University of Hradec Kralove

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50431520BDBM50431520(CHEMBL2348863)
Affinity DataIC50: 2.41E+3nMAssay Description:Inhibition of mTORC2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Celgene

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50431520BDBM50431520(CHEMBL2348863)
Affinity DataIC50: 2.55E+3nMAssay Description:Inhibition of mTOR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50431520BDBM50431520(CHEMBL2348863)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of PI3Kalpha (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50431520BDBM50431520(CHEMBL2348863)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of PI3Kalpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed