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BDBM50432603 CHEMBL2347187::US9296734, 59

SMILES: c1cc(c(cc1NC(=O)c2ccc(cn2)C#N)[C@@]3(C[C@H](OC(=N3)N)C(F)(F)F)CF)F

InChI Key: InChIKey=QCMXWFUAVCHHIA-UHFFFAOYSA-N

Data: 5 IC50

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50432603
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Beta-secretase 1 (Human)	BDBM50432603 (CHEMBL2347187 \| US9296734, 59) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	17.9	n/a	n/a	n/a	n/a	4.2	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Cathepsin D (Human)	BDBM50432603 (CHEMBL2347187 \| US9296734, 59) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>4.00E+5	n/a	n/a	n/a	n/a	3.5	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Beta-secretase 1 (Human)	BDBM50432603 (CHEMBL2347187 \| US9296734, 59) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	37
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Beta-secretase 1 (Human)	BDBM50432603 (CHEMBL2347187 \| US9296734, 59) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Beta-secretase 1 (Human)	BDBM50432603 (CHEMBL2347187 \| US9296734, 59) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair