BDBM50433032 CHEMBL2376096

SMILES COc1ccc(cn1)-c1cc2c(C)nc(N)nc2n([C@H]2CC[C@@H](CC2)OCC(O)=O)c1=O

InChI Key InChIKey=FYGAMXOBXPHZMN-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50433032   

LigandPNGBDBM50433032(CHEMBL2376096)
Affinity DataKi:  0.350nMAssay Description:Inhibition of mouse PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50433032(CHEMBL2376096)
Affinity DataKi:  8.60nMAssay Description:Inhibition of mTOR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
LigandPNGBDBM50433032(CHEMBL2376096)
Affinity DataIC50: 2.07E+3nMAssay Description:Inhibition of AKT phosphorylation at Ser 473 in human BT20 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed