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BDBM50433114 CHEMBL2377395

SMILES: COc1ccc(cc1)C(=O)CCc1coc2cccc(OCC3CCCCC3)c2c1=O

InChI Key: InChIKey=BGVHHOIKSKAZJQ-UHFFFAOYSA-N

Data: 1 IC50

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50433114   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Interleukin-5


(Mus musculus)
BDBM50433114
PNG
(CHEMBL2377395)
Show SMILES COc1ccc(cc1)C(=O)CCc1coc2cccc(OCC3CCCCC3)c2c1=O
Show InChI InChI=1S/C26H28O5/c1-29-21-13-10-19(11-14-21)22(27)15-12-20-17-31-24-9-5-8-23(25(24)26(20)28)30-16-18-6-3-2-4-7-18/h5,8-11,13-14,17-18H,2-4,6-7,12,15-16H2,1H3
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MMDB

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PC sid
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Similars

Article
PubMed
n/an/a 1.60E+4n/an/an/an/an/an/a



Chungnam National University

Curated by ChEMBL


Assay Description
Inhibition interleukin-5 in mouse Y16 cells after 48 hrs by WST-1 assay


Bioorg Med Chem 21: 2543-50 (2013)


Article DOI: 10.1016/j.bmc.2013.02.037
BindingDB Entry DOI: 10.7270/Q2RR20MV
More data for this
Ligand-Target Pair