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BDBM50433391 CHEMBL2375620

SMILES: Oc1ccc(cc1)N1CCN(CC1)c1cc(nc2ccccc12)-c1ccccn1

InChI Key: InChIKey=OQYRBFHDQXGXBC-UHFFFAOYSA-N

Data: 3 EC50

Find this compound or compounds like it in BindingDB or PDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50433391   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Methionine Aminopeptidase Type 1 (MetAP1)


(Homo sapiens (human))
BDBM50433391
PNG
(CHEMBL2375620)
Show SMILES Oc1ccc(cc1)N1CCN(CC1)c1cc(nc2ccccc12)-c1ccccn1
Show InChI InChI=1S/C24H22N4O/c29-19-10-8-18(9-11-19)27-13-15-28(16-14-27)24-17-23(22-7-3-4-12-25-22)26-21-6-2-1-5-20(21)24/h1-12,17,29H,13-16H2
PDB
MMDB

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PC cid
PC sid
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Article
PubMed
n/an/an/an/a 94n/an/an/an/a



Johns Hopkins University School of Medicine

Curated by ChEMBL


Assay Description
Inhibition of human methionine aminopeptidase 1 in presence of Co2+


J Med Chem 56: 3996-4016 (2013)

More data for this
Ligand-Target Pair
Methionine aminopeptidase 2


(Homo sapiens (human))
BDBM50433391
PNG
(CHEMBL2375620)
Show SMILES Oc1ccc(cc1)N1CCN(CC1)c1cc(nc2ccccc12)-c1ccccn1
Show InChI InChI=1S/C24H22N4O/c29-19-10-8-18(9-11-19)27-13-15-28(16-14-27)24-17-23(22-7-3-4-12-25-22)26-21-6-2-1-5-20(21)24/h1-12,17,29H,13-16H2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

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Article
PubMed
n/an/an/an/a>1.00E+5n/an/an/an/a



Johns Hopkins University School of Medicine

Curated by ChEMBL


Assay Description
Inhibition of human methionine aminopeptidase 2 in presence of Mn2+


J Med Chem 56: 3996-4016 (2013)

More data for this
Ligand-Target Pair
Methionine Aminopeptidase Type 1 (MetAP1)


(Homo sapiens (human))
BDBM50433391
PNG
(CHEMBL2375620)
Show SMILES Oc1ccc(cc1)N1CCN(CC1)c1cc(nc2ccccc12)-c1ccccn1
Show InChI InChI=1S/C24H22N4O/c29-19-10-8-18(9-11-19)27-13-15-28(16-14-27)24-17-23(22-7-3-4-12-25-22)26-21-6-2-1-5-20(21)24/h1-12,17,29H,13-16H2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 8.10E+3n/an/an/an/a



Johns Hopkins University School of Medicine

Curated by ChEMBL


Assay Description
Inhibition of human methionine aminopeptidase 1 in presence of Mn2+


J Med Chem 56: 3996-4016 (2013)

More data for this
Ligand-Target Pair