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BDBM50433954 CHEMBL2380909

SMILES: CC(C)c1ccc(CCn2c(O)cc(=O)n(C3CCCC3)c2=O)cc1

InChI Key: InChIKey=NFAOERBTUQTIGQ-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50433954   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Voltage-gated L-type calcium channel alpha-1C subunit


(Oryctolagus cuniculus)
BDBM50433954
PNG
(CHEMBL2380909)
Show SMILES CC(C)c1ccc(CCn2c(O)cc(=O)n(C3CCCC3)c2=O)cc1
Show InChI InChI=1S/C20H26N2O3/c1-14(2)16-9-7-15(8-10-16)11-12-21-18(23)13-19(24)22(20(21)25)17-5-3-4-6-17/h7-10,13-14,17,23H,3-6,11-12H2,1-2H3
PDB
MMDB

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PC cid
PC sid
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Similars

Article
PubMed
n/an/a 5.76E+4n/an/an/an/an/an/a



Northwestern University

Curated by ChEMBL


Assay Description
Antagonist activity at rabbit CaV1.2alpha1C transfected in HEK293 cells by FLIPR assay


J Med Chem 56: 4786-97 (2013)


Article DOI: 10.1021/jm4005048
BindingDB Entry DOI: 10.7270/Q28G8N35
More data for this
Ligand-Target Pair