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BDBM50434327 CHEMBL2386556

SMILES: CN(C)C(=O)[C@H]1C[C@@H]1c1ccc(cc1)-c1nc(C2CC2)n(C)c1Sc1ccc(Cl)cn1

InChI Key: InChIKey=JTNJHVMHCJOQKC-QINVSXPYNA-N

Data: 2 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50434327   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Fatty-acid amide hydrolase 1


(Homo sapiens (Human))
BDBM50434327
PNG
(CHEMBL2386556)
Show SMILES CN(C)C(=O)[C@H]1C[C@@H]1c1ccc(cc1)-c1nc(C2CC2)n(C)c1Sc1ccc(Cl)cn1
Show InChI InChI=1/C24H25ClN4OS/c1-28(2)23(30)19-12-18(19)14-4-6-15(7-5-14)21-24(29(3)22(27-21)16-8-9-16)31-20-11-10-17(25)13-26-20/h4-7,10-11,13,16,18-19H,8-9,12H2,1-3H3/t18-,19+/s2
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 48n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human FAAH expressed in CHO cell lysates assessed as arachidonyl-7-amino-4-methylcoumarin amide hydrolysis to 7-amino 4-methyl coumarin...


ACS Med Chem Lett 4: 509-13 (2013)


Article DOI: 10.1021/ml4000996
BindingDB Entry DOI: 10.7270/Q21R6RWJ
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1


(Rattus norvegicus (rat))
BDBM50434327
PNG
(CHEMBL2386556)
Show SMILES CN(C)C(=O)[C@H]1C[C@@H]1c1ccc(cc1)-c1nc(C2CC2)n(C)c1Sc1ccc(Cl)cn1
Show InChI InChI=1/C24H25ClN4OS/c1-28(2)23(30)19-12-18(19)14-4-6-15(7-5-14)21-24(29(3)22(27-21)16-8-9-16)31-20-11-10-17(25)13-26-20/h4-7,10-11,13,16,18-19H,8-9,12H2,1-3H3/t18-,19+/s2
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 106n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of rat FAAH expressed in CHO cell lysates assessed as arachidonyl-7-amino-4-methylcoumarin amide hydrolysis to 7-amino 4-methyl coumarin p...


ACS Med Chem Lett 4: 509-13 (2013)


Article DOI: 10.1021/ml4000996
BindingDB Entry DOI: 10.7270/Q21R6RWJ
More data for this
Ligand-Target Pair