BDBM50434581 CHEMBL2386595::imatinib-CD3

SMILES [2H]C([2H])([2H])N5CCN(Cc4ccc(C(=O)Nc3ccc(C)c(Nc2nccc(c1cccnc1)n2)c3)cc4)CC5

InChI Key InChIKey=KTUFNOKKBVMGRW-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50434581   

TargetMast/stem cell growth factor receptor Kit(Human)
High Magnetic Field Laboratory

Curated by ChEMBL
LigandPNGBDBM50434581(CHEMBL2386595 | imatinib-CD3)
Affinity DataIC50: 164nMAssay Description:Inhibition of recombinant C-terminal polyhistidine-tagged human c-KIT expressed in mammalian expression system using Tyr 06 peptide as substrate meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2018
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
High Magnetic Field Laboratory

Curated by ChEMBL
LigandPNGBDBM50434581(CHEMBL2386595 | imatinib-CD3)
Affinity DataIC50: 223nMAssay Description:Inhibition of C-terminal His-tagged human ABL1 expressed in baculovirus infected SF9 cells using Tyr 02 peptide as substrate measured after 1 hr by F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2018
Entry Details Article
PubMed