BDBM50434750 CHEMBL2385596
SMILES CN1CCN(CC1)c1ccc(cc1)-c1cnc2c(cnn2c1)-c1ccnc2ccccc12
InChI Key InChIKey=XBGWAKUQSRNWMA-UHFFFAOYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50434750
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataIC50: 75nMAssay Description:Inhibition of ALK5 (unknown origin)More data for this Ligand-Target Pair
TargetBone morphogenetic protein 4(Mus musculus)
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibition of BMP4 in mouse C2C12BRA cells after 14 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetActivin receptor type-1B(Homo sapiens (Human))
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataIC50: 183nMAssay Description:Inhibition of ALK4 (unknown origin)More data for this Ligand-Target Pair
TargetBone morphogenetic protein receptor type-2(Homo sapiens (Human))
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataIC50: 2.36E+3nMAssay Description:Inhibition of BMPR2 (unknown origin)More data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase subunit beta-1(Homo sapiens (Human))
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataIC50: 960nMAssay Description:Inhibition of AMPK (unknown origin)More data for this Ligand-Target Pair
TargetTGF-beta receptor type-2(Homo sapiens (Human))
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of TGFBR2 (unknown origin)More data for this Ligand-Target Pair