BDBM50434816 CHEMBL2387084

SMILES Cc1nnc([nH]1)-c1cn2CCOc3cc(ccc3-c2n1)-c1cnn(CCO)c1

InChI Key InChIKey=DDRRVMBAHALKPP-UHFFFAOYSA-N

Data  1 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50434816   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Genentech

Curated by ChEMBL

LigandBDBM50434816(CHEMBL2387084)Copy SMILESCopy InChI

Affinity DataKi:  21nMAssay Description:Inhibition of PI3Kalpha (unknown origin) assessed as 3,4,5-inositoltriphosphate formation after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
4/13/2014
Entry Details Article
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