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BDBM50435652 CHEMBL2391429

SMILES: CCOC(=O)c1cc(C)nc(Oc2cccc(NS(=O)(=O)c3ccc(Cl)cc3)c2)c1C#N

InChI Key: InChIKey=DNJBKRNTHOLUPB-UHFFFAOYSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50435652   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
G-protein coupled receptor 119 (GPR119)


(Homo sapiens (Human))
BDBM50435652
PNG
(CHEMBL2391429)
Show SMILES CCOC(=O)c1cc(C)nc(Oc2cccc(NS(=O)(=O)c3ccc(Cl)cc3)c2)c1C#N
Show InChI InChI=1S/C22H18ClN3O5S/c1-3-30-22(27)19-11-14(2)25-21(20(19)13-24)31-17-6-4-5-16(12-17)26-32(28,29)18-9-7-15(23)8-10-18/h4-12,26H,3H2,1-2H3
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 13n/an/an/an/a



Amgen Inc

Curated by ChEMBL


Assay Description
Agonist activity at human GPR119 expressed in HEK293 cells assessed as cAMP accumulation after 30 mins


Bioorg Med Chem Lett 23: 3609-13 (2013)


Article DOI: 10.1016/j.bmcl.2013.04.014
BindingDB Entry DOI: 10.7270/Q2K938XJ
More data for this
Ligand-Target Pair