BDBM50437171 CHEMBL2401813

SMILES C[C@@H](Oc1c(N)ncc2c(coc12)-c1cnn(c1)C1CCNCC1)c1c(Cl)ccc(F)c1Cl

InChI Key InChIKey=RFKWZWJQRQCLJF-GFCCVEGCSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50437171   

TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50437171(CHEMBL2401813)
Affinity DataIC50:  47nMAssay Description:Inhibition of cMET (unknown origin) using biotinylated poly(Glu,Tyr) as substrate after 60 minsMore data for this Ligand-Target Pair
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50437171(CHEMBL2401813)
Affinity DataIC50:  410nMAssay Description:Inhibition of cMET in human MKN45 cells assessed as phosphorylated MET levels after 4 hrsMore data for this Ligand-Target Pair