BDBM50437211 CHEMBL2402732

SMILES CC(C)(C)C[C@@H]1N[C@H]([C@H](c2cccc(Cl)c2F)[C@@]1(C#N)c1ccc(Cl)cc1F)C(=O)Nc1ccc(cn1)C(O)=O

InChI Key InChIKey=KCLGOJLRKLTZEP-PSAGRBGJSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50437211   

TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50437211(CHEMBL2402732)
Affinity DataIC50:  23nMAssay Description:Binding affinity to GST-tagged MDM2 (unknown origin) assessed as inhibition of interaction with p53 after 1 hr by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed