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BDBM50437423 CHEMBL2409010

SMILES: CCCc1c(cnn1-c1ncc(C)c(n1)-c1cccs1)C(=O)NCc1cn(C)cn1

InChI Key: InChIKey=SVVOUQZKBGAKJS-UHFFFAOYSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50437423   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Probable G-protein coupled receptor 142


(Homo sapiens (Human))
BDBM50437423
PNG
(CHEMBL2409010)
Show SMILES CCCc1c(cnn1-c1ncc(C)c(n1)-c1cccs1)C(=O)NCc1cn(C)cn1
Show InChI InChI=1S/C21H23N7OS/c1-4-6-17-16(20(29)22-10-15-12-27(3)13-24-15)11-25-28(17)21-23-9-14(2)19(26-21)18-7-5-8-30-18/h5,7-9,11-13H,4,6,10H2,1-3H3,(H,22,29)
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 1.50E+4n/an/an/an/a



Daiichi Sankyo Co., Ltd.

Curated by ChEMBL


Assay Description
Agonist activity at human GPR142 transfected in HEK293 cells after 1 hr by inositol phosphate accumulation assay


ACS Med Chem Lett 4: 790-4 (2013)


Article DOI: 10.1021/ml400186z
BindingDB Entry DOI: 10.7270/Q24J0GHW
More data for this
Ligand-Target Pair