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BDBM50437563 CHEMBL2407516

SMILES: CN(C)CCNCCNc1ccc2C(=O)N(C)C(=O)c3cccc1c23

InChI Key: InChIKey=RNJZBFCKSYWVBR-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50437563   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Platelet-derived growth factor receptor


(Homo sapiens (Human))
BDBM50437563
PNG
(CHEMBL2407516)
Show SMILES CN(C)CCNCCNc1ccc2C(=O)N(C)C(=O)c3cccc1c23
Show InChI InChI=1S/C19H24N4O2/c1-22(2)12-11-20-9-10-21-16-8-7-15-17-13(16)5-4-6-14(17)18(24)23(3)19(15)25/h4-8,20-21H,9-12H2,1-3H3
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



East China University of Science and Technology

Curated by ChEMBL


Assay Description
Inhibition of PDGFRalpha (unknown origin) using poly (Glu, Tyr)4:1 as substrate by ELISA


Eur J Med Chem 65: 477-86 (2013)


Article DOI: 10.1016/j.ejmech.2013.05.002
BindingDB Entry DOI: 10.7270/Q2B27WQ7
More data for this
Ligand-Target Pair
Platelet-derived growth factor receptor beta


(Homo sapiens (Human))
BDBM50437563
PNG
(CHEMBL2407516)
Show SMILES CN(C)CCNCCNc1ccc2C(=O)N(C)C(=O)c3cccc1c23
Show InChI InChI=1S/C19H24N4O2/c1-22(2)12-11-20-9-10-21-16-8-7-15-17-13(16)5-4-6-14(17)18(24)23(3)19(15)25/h4-8,20-21H,9-12H2,1-3H3
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



East China University of Science and Technology

Curated by ChEMBL


Assay Description
Inhibition of PDGFRbeta (unknown origin) using poly (Glu, Tyr)4:1 as substrate by ELISA


Eur J Med Chem 65: 477-86 (2013)


Article DOI: 10.1016/j.ejmech.2013.05.002
BindingDB Entry DOI: 10.7270/Q2B27WQ7
More data for this
Ligand-Target Pair