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BDBM50438501 CHEMBL2414821

SMILES: COc1cc(\C=C\C(=O)NC[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)ccc1O

InChI Key: InChIKey=JLYHRVLBDKDBLM-RXIPOPCKNA-N

Data: 3 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50438501   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Acidic alpha-glucosidase


(Rattus norvegicus)
BDBM50438501
PNG
(CHEMBL2414821)
Show SMILES COc1cc(\C=C\C(=O)NC[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)ccc1O
Show InChI InChI=1/C17H23NO8/c1-25-11-6-9(2-4-10(11)20)3-5-14(21)18-7-12-15(22)17(24)16(23)13(8-19)26-12/h2-6,12-13,15-17,19-20,22-24H,7-8H2,1H3,(H,18,21)/b5-3+/t12-,13+,15-,16+,17+/s2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.82E+5n/an/an/an/an/an/a



Xi'an Jiaotong University

Curated by ChEMBL


Assay Description
Inhibition of rat intestinal maltase using maltose as substrate assessed as D-glucose release from substrate preincubated for 15 mins measured after ...


Bioorg Med Chem 21: 5442-50 (2013)


Article DOI: 10.1016/j.bmc.2013.06.002
BindingDB Entry DOI: 10.7270/Q2HD7X24
More data for this
Ligand-Target Pair
alpha-Glucosidase (α-Glucosidase)


(Rattus norvegicus (Rat))
BDBM50438501
PNG
(CHEMBL2414821)
Show SMILES COc1cc(\C=C\C(=O)NC[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)ccc1O
Show InChI InChI=1/C17H23NO8/c1-25-11-6-9(2-4-10(11)20)3-5-14(21)18-7-12-15(22)17(24)16(23)13(8-19)26-12/h2-6,12-13,15-17,19-20,22-24H,7-8H2,1H3,(H,18,21)/b5-3+/t12-,13+,15-,16+,17+/s2
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.53E+5n/an/an/an/an/an/a



Xi'an Jiaotong University

Curated by ChEMBL


Assay Description
Inhibition of rat intestinal sucrase using sucrose as substrate assessed as D-glucose release from substrate preincubated for 15 mins measured after ...


Bioorg Med Chem 21: 5442-50 (2013)


Article DOI: 10.1016/j.bmc.2013.06.002
BindingDB Entry DOI: 10.7270/Q2HD7X24
More data for this
Ligand-Target Pair
α-glucosidase


(Saccharomyces cerevisiae S288c (Baker's yeast))
BDBM50438501
PNG
(CHEMBL2414821)
Show SMILES COc1cc(\C=C\C(=O)NC[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)ccc1O
Show InChI InChI=1/C17H23NO8/c1-25-11-6-9(2-4-10(11)20)3-5-14(21)18-7-12-15(22)17(24)16(23)13(8-19)26-12/h2-6,12-13,15-17,19-20,22-24H,7-8H2,1H3,(H,18,21)/b5-3+/t12-,13+,15-,16+,17+/s2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.02E+5n/an/an/an/an/an/a



Xi'an Jiaotong University

Curated by ChEMBL


Assay Description
Inhibition of Saccharomyces cerevisiae alpha-glucosidase assessed as 4-nitrophenol release from 4-nitrophenyl alpha-D-glucopyranoside preincubated fo...


Bioorg Med Chem 21: 5442-50 (2013)


Article DOI: 10.1016/j.bmc.2013.06.002
BindingDB Entry DOI: 10.7270/Q2HD7X24
More data for this
Ligand-Target Pair