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BDBM50438690 CHEMBL2414563

SMILES: CCC(=O)Nc1nc2cccc(-c3cccc(c3)C(C)C)n2n1

InChI Key: InChIKey=UWMHLPUYSARZSL-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50438690   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine-protein kinase JAK2


(Homo sapiens (Human))
BDBM50438690
PNG
(CHEMBL2414563)
Show SMILES CCC(=O)Nc1nc2cccc(-c3cccc(c3)C(C)C)n2n1
Show InChI InChI=1S/C18H20N4O/c1-4-17(23)20-18-19-16-10-6-9-15(22(16)21-18)14-8-5-7-13(11-14)12(2)3/h5-12H,4H2,1-3H3,(H,20,21,23)
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PC cid
PC sid
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Similars

Article
PubMed
2.20E+3n/an/an/an/an/an/an/an/a



Genentech

Curated by ChEMBL


Assay Description
Inhibition of JAK2 (unknown origin)


Bioorg Med Chem Lett 23: 5014-21 (2013)


Article DOI: 10.1016/j.bmcl.2013.06.008
BindingDB Entry DOI: 10.7270/Q29S1SF2
More data for this
Ligand-Target Pair